Effects of 1-year weight loss intervention on abdominal skeletal muscle mass in Japanese overweight men and women

Noriko I Tanaka ； Haruka Murakami ； Naomi Aiba ； Akemi Morita ； Shaw Watanabe ； Motohiko Miyachi ； Saku Control Obesity Program (SCOP) Study Group)

《Asia Pacific Journal of Clinical Nutrition》 28卷1期 (2019/03) Pp. 72-78

https://doi.org/10.6133/apjcn.201903_28(1).0011

摘要

Background and Objectives: Limited information is available on how weight loss intervention programs affect skeletal muscle mass especially in trunk. Methods and Study Design: A total of 235 overweight Japanese men and women aged 40-64 years with a body mass index of 28.0 to 44.8 kg/m^2 participated in this randomized controlled intervention study. They were randomly divided into a lifestyle intervention group and control group. Before and after the one-year lifestyle intervention for weight loss an abdominal transverse image was acquired by computed tomography. The cross-sectional areas (CSAs) of visceral fat, subcutaneous fat, and skeletal muscle of rectus abdominis, abdominal oblique, iliopsoas, and erector spinae muscle were calculated. Results: The body weight changed by approximately -5% in the intervention groups. The corresponding values for subcutaneous fat and visceral fat CSAs were -10.8 to -17.5% in both sexes. The reductions observed in skeletal muscle CSAs were significantly less (-6.0% and -7.2% in the men and women intervention groups respectively) than those in fat tissue CSAs. The CSA of each of the four skeletal muscle groups also significantly decreased; however, after adjustments for body weight at each time point, only reductions in the iliopsoas muscle in both sex and abdominal oblique muscles in men remained significant. Conclusions: The lifestyle weight loss intervention might reduce the relative amount of the abdominal skeletal muscles especially in iliopsoas muscle.

關鍵字

muscle distribution ； life style intervention ； weight loss ； visceral fat ； middle-aged ； Japanese