Maternal diet during pregnancy and infant respiratory morbidity: A prospective study

Kai Ning Chong ； Hui Chean E ； Rafdzah Ahmad Zaki ； Siti Hawa Mohd Taib ； Hazreen Abdul Majid ； Ai Kah Ng ； Kah Peng Eg ； Shih Ying Hng ； Cindy Shuan Ju Teh ； Nuguelis Razali ； Anna Marie Nathan ； Jessie Anne de Bruyne

《Asia Pacific Journal of Clinical Nutrition》 30卷4期 (2021/12) Pp. 632-642

https://doi.org/10.6133/apjcn.202112_30(4).0010

摘要

Background and Objectives: Maternal diet during pregnancy may impact infant respiratory morbidity. The aim was to determine the association between antenatal maternal diet and respiratory morbidity of their infants during their first 6 months of life. Methods and Study Design: This prospective cohort study included healthy mother-infant pairs. Maternal diet during the last trimester was determined with a validated food frequency questionnaire. Infant respiratory morbidity was solicited at 1, 3 and 6 months. Results: Three hundred mother-baby pairs were recruited. Maternal consumption of milk and dairy products was associated with reduced respiratory symptoms at 1 month (aOR 0.29 [95% CI: 0.10, 0.86], p=0.03) and 3 months old (aOR 0.43 [95% CI: 0.20, 0.93], p=0.03), while intake of confectionery items was associated with increased unscheduled doctor visits at 3 months (aOR 2.01 [95% CI 1.33, 3.06], p=0.001) and increased nebuliser treatment at both 3 months (aOR 1.88 [95% CI 1.12, 3.17], p=0.02) and 6 months (aOR 1.64 [95% CI 1.05, 2.54], p=0.03). Finally, at 6 months, hypertensive disorders during pregnancy was associated with increased nebuliser treatment (aOR 17.3 [95% CI 1.50, 199], p=0.02) while exclusive breastfeeding was associated with reduced incidence of respiratory symptoms (OR 0.47 [95% CI 0.26, 0.83], p=0.01). Conclusions: Increased antenatal maternal consumption of milk and dairy products may reduce respiratory morbidity while increased consumption of confectionery items may increase respiratory morbidity in their infants during the first 6 months of life.

關鍵字

Malaysia ； infection ； antenatal ； diet ； respiratory tract