- 期刊
- OpenAccess
Pimary Hyperparathyroidism as Central Giant Cell Granuloma of the Jaws: Preand Posttreatment Pattern of Clinical and Radiographic Presentation
並列摘要
Introduction: The parathyroid glands regulate serum calcium and phosphorous levels by its secretion and maintenance, within physiological limits, of its hormone parathormone (PTH). Hyperparathyroidism is a metabolic disorder resulting from excessive secretion of parathyroid hormone. Hyper secretion might occur either due to a primary pathology in the glands (or) due to secondary causes. Central giant cell lesions occur in jaw bones. Case Report: A 20-year-old boy reported with complaints of swelling in left maxilla. Intra orally swelling extended from left upper canine till left upper second premolar and caused expansion of the cortical plates. Intra oral radiograph and orthopantomograph showed a poorly defined radiolucent lesion in between left upper canine and left upper 1st premolar with multiple cystic cavities in the region of the symphysis, left body and right angle of mandible. The radiographs of long bones showed osteoporosis. Serum alkaline phosphatase level was raised. Histopathology was reported as central giant cell granuloma. Nuclear scan of parathyroid showed a functioning parathyroid adenoma. The swelling in left maxilla regressed on its own after the adenoma of the parathyroids was excised. Conclusion: Timely diagnosis of parathyroid adenoma results in total regression of intra oral swelling and further progression of osteoporosis and fractures of long bones can be prevented.
延伸閱讀
- Chuang, T. C., Chang, J. M., Hwang, S. J., Hsiao, P. J., & Lai, Y. H. (1998). A Patient of Primary Hyperparathyroidism with Full-Blown Bone Changes Simulating Malignancy. The Kaohsiung Journal of Medical Sciences, 14(9), 584-589. https://doi.org/10.6452/KJMS.199809.0584
- Kao, C. H., Lin, W. Y., & Wang, S. J. (1992). Comparison between Thallium-Technetium Substraction Scan and Other Imaging Modalities in the Preoperative Localization of Abnormal Parathyroid Glands. The Kaohsiung Journal of Medical Sciences, 8(5), 272-276. https://doi.org/10.6452/KJMS.199205.0272
- HannahWinter, Field, M., McDaid, J., Vishwanath, D., & Inston, N. (2012). Primary Hyperparathyroidism Presenting as Paraneoplastic Syndrome in a Patient with Renal Cell Carcinoma. International Journal of Case Reports and Images (IJCRI), 3(4), 19-22. https://doi.org/10.5348/ijcri-2012-4-108-CR-5
- Khan, A., Khan, Y., Raza, S., Akbar, G., Khan, M., Diwan, N., & Rizvi, W. (2012). Functional Parathyroid Cyst: A Rare Cause of Malignant Hypercalcemia with Primary Hyperparathyroidism-A Case Report and Review of the Literature. Case Reports in Medicine, 2012(), 54-58-309. https://doi.org/10.1155/2012/851941
- Chang, H. H., Chou, F. F., Hsu, C. C., & Wang, P. W. (2015). Undescended Parathyroid Gland: A Rare but Potential Cause of Persistent or Recurrent Hyperparathyroidism. 核子醫學暨分子影像雜誌, 28(2), 79-85. https://doi.org/10.6332/ANMMI.2802.004