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Human Metapneumovirus Treated with Inhaled Ribavirin: A Case Report

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Introduction: Human metapneumovirus is a new pulmonary pathogen in the Paramyxoviridae family. It is increasingly associated with respiratory illnesses particularly in immunocompromised patients. We report a case of a multiple myeloma patient diagnosed with human metapneumovirus pneumonia and successfully treated with inhaled ribavirin. Case Report: A 56-yearold white female with previously diagnosed multiple myeloma presented with fever, nonproductive cough, dyspnea and new onset ground glass opacities on computed tomography scan. Human metapneumovirus was detected in bronchoalveolar lavage specimen with direct fluorescent antibody testing. Marked clinical improvement was observed following a fiveday course of inhaled ribavirin. Conclusion: Human metapneumovirus can cause community acquired pneumonia in immunocompromised patients presenting with lower respiratory tract illness. It is associated with significant morbidity and mortality in this population. Early diagnosis and prompt treatment with inhaled ribavirin may improve outcomes in immunocompromised patients.

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