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飲水加氟對大白鼠牙齒發育之影響
Deleterious Effect of Fluoridated Water on the Developing Dental Tissues of Rat
並列摘要
Effect of fluoride in drinking water on the developing dental tissues was studied on rats. Forty Long-Evans rats were given drinking water containing fluoride at different concentrations (0,1,5 and 20 ppm) for varying durations. The gross examination of the teeth of each rat, after sacrifice revealed no apparent mottling or dysplastic defects, but demonstrated reduced caries incidence in fluoride-treated rats. Both hypoplastic and hypocalcified tissue changes were found in ground and paraffin sections of the teeth of rats receiving fluoride. Various combinations of the developmental abnormalities were observed, and consisted of thin enamel, microdefects, exaggerated incremental lines, interglobular dentin, degenerated odontoblasts and ameloblasts, malformation or malcalcification of both the matrix and the matured hard dental tissues, thick predentin and pulp hyperemia. The mechanism of the response of dental tissues to chronic fluoride intoxication was discussed. A combined measure of low concentration water fluoridation and topical application of fluoride was suggested as optimal in caries prevention.
並列關鍵字
無資料延伸閱讀
- 洪鈺卿（1978）。飲水加氟與蛀牙預防及其安全性。中華民國營養學會雜誌，3(2)，20-21。https://doi.org/10.6691/JCNS.197809_3(2).0004
- 文昌（1993）。認試飲水加氟的防齲作用。師友月刊，(316)，52-52。https://doi.org/10.6437/EM.199310.0052
- 徐奎望（1978）。飲水加氟有致癌作用嗎？喝茶能防蛀牙嗎？。中華民國營養學會雜誌，3(2)，22-22。https://doi.org/10.6691/JCNS.197809_3(2).0005
- Sun, K. T., Feng, C. C., Chan, Y. C., Liu, Y. L., & Chiang, H. H. (2012). 氟漆對於學齡前兒童唾液內變異型鏈球菌之影響. 臺灣兒童牙醫學雜誌, 12(1), 54-59. https://doi.org/10.6319/TJPD.2012.12(1).9
- 魏心怡（2011）。Effect of electrolyzed water on physical properties of the superficial dentin〔碩士論文，高雄醫學大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0011-1807201122483600