原發性副甲狀腺機能亢進症乃是一個或多個副甲狀腺腺體發生不正常的細胞增生引致副甲狀腺激素過度的分泌而造成之疾患。三軍總醫院在過去三十年內病理證實之原發性副甲狀腺機能亢進症僅五例且均為腺瘤,茲將其中二例提出;一例同時併有甲狀腺結節性腫大,另一例則先前有惡性腫瘤。特將其臨床特點,診斷作一討論式的報告。
Hyperparathyroidism is a disorder charecterized by excessive secretion of the parathyroid hormone (PTH) by one or more glands that have undergone abnormal cellular proliferation, either as a primary event or in response to other physiologic abnormalities. There have been five pathologically proved parathyroid adenoma at TSGH in the past three decades, two were just diagnosed in the past year. We present these two cases; one was accompanied by thyroid nodular goiter, the other was dissociated from the underlying malignancy which was diagnosed as breast adenocarcinoma one year previously.We discuss the application of both long-established and recently developed methods to the diagnosis of hyperparathyroidism, and pay particular attention to the primary disorder.