原發性快速進行性腎絲球腎炎－3病例報告

Idiopathic Rapidly Progressive Glomerulonephritis: Report of Three Cases

張峯義(Feng-Yee Chang) ； 馮祥華(Shyang-Hwa Ferng) ； 侍台平(Tai-Pin Shyh) ； 謝善德(Shang-Der Shieh) ； 黃漢文(Han-Wen Hung) ； 陳安(Ann Chen) ； 何逸僊(Yat-Sen Ho) ； 杜炎昌(Yan-Chang Tu)

《Journal of Medical Sciences》 5卷5期 (1985/03) Pp. 2167-2175

摘要

本報告提出三軍總醫院迄今確定診斷為原發性快速進行性腎絲球腎炎的病例三例。其中二例為Glassock氏分類第三型，另一例為Glassock氏分類第一型（即抗腎絲球基膜抗體疾病，但無肺出血者）。其腎組織都顯示有廣泛性腎絲球新月形成，其中一例多於80%的腎絲球有新月，另兩例則為100%。他們都是年輕男性、都有輕微貧血、高血壓、蛋白尿、血尿、血清中肌氨酸酐大於10mg/dl、並且都處在末期腎衰竭。兩例病人接受Methylprednisolone衝擊療法，但都沒效而接受規則的血液透析術治療；另一例只接受加強性的血液透析治療，但於住院後84天死亡。

關鍵字

腎絲球腎炎

並列摘要

Three cases of idiopathic rapidly progressive glomerulonephritis in our hospital were presented. Two of them were Glassock's type II, one was Glassock's type I (Anti-GBM disease, without pulmonary hemorrhage). The histology showed extensive glomerular crescent formation-one with more than 80%, and two with 100%. They were all young man, all showed mild anemia, hypertension, proteinuria, hematuria, serum creatinine more than 10 mg/dL, and in terminal renal failure. Two cases received methylprednisolone pulse therapy without effeci and were undergone chronic hemodialysis; the other one received only intensive hemodialysis and died on the 84th hospital day.

並列關鍵字

Glomerulonephritis