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Merkel Cell (Neuroendocrine) Carcinoma: Report of Two Cases and Literature Review

Merkel細胞癌:病例報告及文獻回顧

摘要


Merkel細胞癌是一種罕見的原發性皮膚惡性腫瘤。本文報告二例這類少見的皮膚惡性腫瘤,針對其組織病理變化、免疫組織化學特性,包括cytokeratin,neuron-specific enolase及顯微形態加以討論,並作文獻回顧。

並列摘要


We report here two rare cases of primary Merkel cell carcinoma (MCC) of the skin. The tumor was observed to exhibit characteristic immunohistochemical (coexpression of cytokeratin and neuron-specific enolase) and ultrastructural (dense core granules and a globular aggregate of intermediate filaments) features. We have also reviewed the literature concerning the patients with MCC.

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