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Unique Case of Androgen-Producing Hilus Cell Tumor of the Ovary

Hilus細胞瘤:病例報告及文獻回顧

摘要


Hilus細胞瘤是一種罕見的原發性卵巢良性腫瘤,這類少見的腫瘤會因過度分泌睪脂酮(testosterone)而導致病人有男性化傾向。病例報告一73歲女性因禿頭及多毛症至本院求診,經血液分析及骨盆腔超音波檢查,懷疑為卵巢腫瘤,經輸卵管切除術後確定為hilus細胞瘤。術後一星期追蹤血中睪脂酮(testosterone)恢復正常。本文針對病理及臨床特徵加以討論並作文獻回顧。

關鍵字

卵巢 hilus細胞瘤 Reinke結晶

並列摘要


The case of hilus cell tumor of the ovary occurs rarely. The hallmark feature of the hilus cell tumor is virilization because of testosterone overproduction by this neoplasm. A 73-year-old postmenopausal woman with high plasma testosterone levels and virilization was demonstrated by frontal balding, hirsutism, acne and hoarseness. Investigation of the cause of virilization on this patient revealed an elevated serum testosterone level and an increased left ovary. Following bilateral salpingo-oophorectomy, a 3.0 x 2.0 x 1.5 cm left ovary was found to contain a hilus (Leydig) cell tumor. One week after operation, the testosterone level was 0.8 ng/ml (1.8 to 7.58 ng/ml). The related literature concerning the clinicopathological features of hilus cell tumor was also reviewed.

並列關鍵字

ovary hilus cell tumor Reinke crystal

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