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Primary Non-Hodgkin's Lymphoma of Bone Presenting as Thoracic Spinal Compression Fracture: A Case Report and Literature Review
原發性非何杰金氏骨淋巴瘤之胸椎壓迫性骨折：案例報告及文獻回顧
並列摘要
Here we report a non-Hodgkin's lymphoma (NHL) with initial manifestation as spinal cord compression fracture. A 23-year-old male presented to our emergency room with refractory lower back pain and deteriorating neurological presentations. An intraspinal tumor of the 12(superscript th) thoracic vertebral body causing a total compression fracture was confirmed. Result of tissue biopsy and PET scan proved NHL without nodal involvement. Eight courses of anti-CD20 monoclonal antibody combined with chemotherapy, but without radiotherapy which was taken as the standard treatment in primary bone lymphoma, were prescribed. The patient survived for 3 years without tumor recurrence. Anti-CD20 monoclonal antibody, instead of radiotherapy, may provide an alternative treatment of choice for patients with primary bone lymphoma (PBL).
延伸閱讀
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