McCune-Albright Syndrome with Pathologic Compression Fracture of the Vertebrae: Report of a Case with Imaging Manifestations

McCune-Albright症候群合併胸腰椎病理壓迫性骨折之各種影像之特徵：病例報告

劉大忠(Da-Chung Liou) ； 陸教義(Chiao-Yi Lu)

《中華放射線醫學雜誌》 30卷3期 (2005/06) Pp. 183-187

摘要

McCune-Albright症候群是一個廣泛多發性的纖維發育異常，合併皮膚的咖啡斑和內分泌異常導致性早熟的總稱。它好發單側並且在影像學上有特殊的表現，我們的病例是一個18歲的男性，由於侵犯到頭顱、兩側肋骨、全身脊椎、左側骨盆、合併脊椎側彎和病理壓迫性骨折，加上身上的斑點和性早熟的外觀，而被證實是McCune-Albright症候群，由於是少見的先天性異常疾病，因此我們作了一系列不同的影像來評估這種疾病。

關鍵字

纖維發育異常 ； McCune-Albright症候群 ； 脊椎、骨折

並列摘要

We describe an 18 year-old man with unusually extensive polyostotic fibrous dysplasia, which associated with scoliosis of the thoracic spine and pathologic compression fractures of T8-9, L1, and L3. Because of extensive involvement of the spine, thoracic costae, left pelvic bones and femur as well as endocrine dysfunction and skin pigmentation, he was admitted for surgery. Plain radiographs and computed tomographic scans showed expansile osteolytic lesions of the bilateral thoracic costae.
These lesions presented with intermediate signal intensity on T1-weighted magnetic resonance images, hyperintensity on T2-weighted images, and faint enhancement on gadolinium-enhanced T1-weighted images. These clinical and imaging findings may be useful in the diagnosis of McCune-Albright syndrome.

並列關鍵字

Bone, Fibrous dysplasia ； McCune-Albright syndrome ； Spine, fractures