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Primary Retroperitoneal Mucinous Cystadenoma: Report of a Case

原發性後腹膜腔黏液性囊腺瘤:病例報告

摘要


原發性後腹膜腔黏液性囊腺瘤病例甚爲罕見,這類腫瘤的發生原因仍未確定,通常發生在婦女,且與卵巢組織沒有關聯性。我們報告一例發生在一位52歲女性後腹膜腔的巨大黏液性囊腺瘤,此腫瘤經外科完整切除後,顯微鏡下檢視發現其內壁是由問皮細胞及良性分泌黏液之腺體細胞覆蓋。這個發現顯示原發性後腹膜腔黏液性囊腺瘤可能是由體腔問皮細胞經腺體化增生而轉變成黏液分泌細胞。免疫化學染色發現間皮細胞表現出雌激素受體。此一現象顯示黏液性囊腺瘤的生長係受雌激素調控,並可以解釋此一腫瘤好發於女性之原因。

關鍵字

無資料

並列摘要


Primary retroperitoneal mucinous cystadenomas are extremely rare. They are unattached to the ovary and found almost exclusively in women. The pathogenesis of such neoplasms remains uncertain. Herein, we describe a 52-year-old woman who had an en bloc resection of a large retroperitoneal cystic tumor. Microscopic examination of the lining epithelial cells showed features of mesothelial cells in addition to a benign mucinous cystadenoma. These findings suggest that the tumor developed from mucinous metaplasia of the coelomic mesothelium. The mesotheliallike epithelium was positive for estrogen receptors, implicating its role in tumor promotion and the almost exclusive occurrence of such tumors in women.

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