- 期刊
Prevalence of Atrial Fibrillation in Patients with Brugada Syndrome in Taiwan
並列摘要
Purpose: The aim of this study was to assess the prevalence of atrial fibrillation (AF) in patients with Brugada syndrome (BrS) and their clinical characteristics in Taiwan.Methods: The patient group consisted of 47 symptomatic BrS patients consecutively enrolled from 2000 to 2010. The definition of BrS patients with AF was a BrS patient with at least one episode of AF in a 12-lead electrogram or 24-hour holter (permanent, persistent or paroxysmal) during follow-up, or before diagnosis of BrS.Results: Six BrS patients were identified with AF, and all of them were male. Two experienced sudden cardiac death (SCD), 2 presented with seizure and 4 with syncope. The mean age at onset of BrS was 47±16 years, similar to those BrS patients without AF (45±14, P = 0.67). Compared to those BrS patients without AF, significantly higher percentages of the BrS patients with AF presented with seizure and documented ventricular tachyarrhythmia (p = 0.02 and 0.03, respectively). Five of them had spontaneous Brugada type I electrogram, similar to those BrS patients without AF (p = 0.9). The SCN5A mutation rate is similar between BrS patients with AF and those without AF (p = 0.69). The prevalence of AF in BrS patients in Taiwan was 12.7% (6/47, 95% confidence interval 0.06-0.19) which is not significantly lower than the 20% prevalence found in the Caucasian population (p = 0.16).Conclusions: BrS patients with AF had distinct clinical features from those patients without AF in Taiwan.
延伸閱讀
- Tung, Y. C., Wu, L. S., Chen, W. J., Kuo, C. T., Wang, C. L., Chang, C. J., Tsai, H. Y., Yeh, Y. H., & Hsu, L. A. (2013). C-Reactive Protein Gene Polymorphisms and the Risk of Atrial Fibrillation in a Chinese Population in Taiwan. Acta Cardiologica Sinica, 29(3), 208-216. https://www.airitilibrary.com/Article/Detail?DocID=10116842-201305-201305300047-201305300047-208-216
- Hiari, N. (2011). Surgical Treatment of Atrial Fibrillation: A Review. Cardiology Research and Practice, 2011(), 152-157-019. https://doi.org/10.4061/2011/214940
- 許曉溱（2012）。Derivation and validation for adjusting for risk of mortality-the case of acute myocardial infarction in Taiwan〔碩士論文，國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2012.02033
- Sabzi, F., Zokaei, A. H., & Moloudi, A. R. (2011). Predictors of Atrial Fibrillation Following Coronary Artery Bypass Grafting. Clinical Medicine Insights: Cardiology, 2011(), 67-75. https://doi.org/10.4137/CMC.S7170
- Wang, L. Y., Lee, K. T., Lin, C. P., Hsu, L. A., Wang, C. L., Hsu, T. S., & Ho, W. J. (2017). Long-Term Survival of Patients with Pulmonary Arterial Hypertension at a Single Center in Taiwan. Acta Cardiologica Sinica, 33(5), 498-509. https://doi.org/10.6515/ACS20170612A