Synovial Sarcoma: Analysis of 17 Cases with Review of Literatures

台大醫院自1976年至1988年共計有17例滑液囊肉瘤病例；其中男性6位，女性11位。病患的平均年齡26.1歲，範圍目1歲到66歲都有。這些個案追治療的時間自1年到10年不等，平均為3年。在這17例病例中，2/3的個案發生於30歲以前。而其中有95%發生於四肢，而在下肢的佔有76%。在94%的病患，其最主要的症狀為軟組織腫瘤。在絕大部分的病患其普遍的X光檢查為負性。有4位病人到了台大醫院時已有遠處腫瘤轉移的現象，在這有4位病人均接受了全身性的化學治療，而其中一位更換接受了局部的放射線治療。這4位患在2至25個月中均全部死亡。其它13位病患接受了大範圍的切除術(4例)或是局部切除術治療(9例)，術後部份有病人並接受化學治療或是放射線治療。而在這13位病患中，其5年存活率為40%；有60%病患有局部腫瘤復發，而有67%病人有遠處腫瘤轉移現象。這種腫瘤其生長速度一般說來相當媛慢；當有遠處轉移時，最好發於肺部，其它如淋巴腺轉移及肝臟轉移亦有所聞。滑液囊肉瘤在局部切除後其有的機率相當高，因此其最佳的治療方法為的腫瘤切除術或考是截肢術。

關鍵字

無資料

並列摘要

A study of 17 of synovial sarcoma treated from 1976 to 1988 has been made. The male to fmale ratio was 6 to 11. Mean age of patients was 26.1 years, with a range from one year to 66 years. The follow-up period ranged from one year to 10 years with an average of3years. Of the 17 cases, two-third were in the first three decades of life. The extremities were involved in 94% of the cases, while 76% of the lesions occurred in the lower extremity. Soft tissue mass was he most common presenting symptom in 94% patients. Plain roentogenofram shows negative finding in most cases. Four patients Visites our hospital with distant metastasis. All of them received systemic chemotherapy and one also received local radiotherapy. All 4 cases expired within 2 to 25 months. The other 13 patients received wide resection (4 cases) or local excision (9 cases) of tumor with or without chemotherapy or radiotherapy. The overall 5 year survival rate was 40%. Sixty percent had local recurrence and 67% distant metastasis. The tumor usually grows inciduously. Metastasis, when present, usually occurs to the lungs, but lymphogenous spread and liver metastasis were also notes. Local excision was associated with a high recurrent rate and distant metastasis. The recommended treatment is radical resection or amputation.

並列關鍵字

synovial sarcoma ； adical excision ； amputation ； radiotherapy ； chemotherapy

國際替代計量

Synovial Sarcoma: Analysis of 17 Cases with Review of Literatures

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