An iliopsoas abscess is a relatively uncommon condition with a vague clinical presentation. It has an insidious onset, and a definite diagnosis cannot be made without computed tomography or magnetic resonance imaging. We report a middle-aged woman with avascular necrosis (AVN) of the left femoral head and an ipsilateral iliopsoas abscess. Her left femoral-head AVN had been diagnosed for 6 months, and hip arthroplasty was scheduled. However, when the patient was admitted for surgery, she had a mild fever and severe pain during hip flexion. The operation was delayed, and further investigations were done to rule out septic arthritis. On the third day of her admission, a prominent, soft, and tender mass appeared over her left groin area. Computed tomography showed an iliopsoas abscess near the left hip joint. Further investigation did not reveal any association between the abscess formation and the AVN lesion. The abscess was surgically drained, and antibiotic therapy was given. Three months later, total arthroplasty of the left hip was performed, without infection. After another 3 months, total arthroplasty of the right hip was performed.