Renal lymphoma is in general secondary to lymphomatous infiltration of the kidneys in disseminated lymphoma. Occult renal lymphoma clinically mimicking renal medical disease constitutes a diagnostic challenge to nephrologists, radiologists, and oncologists. The clinical and radiological findings, mostly nonspecific or inconclusive, seldom obviate the need for a renal biopsy. Here, we describe a 69-year-old man presenting with enlargement of bilateral kidneys. Physical examination and image studies revealed enlarged lymph nodes at para-aorta area. Under high suspicion of systemic infiltrative diseases involving bilateral kidneys because of atypical renal images, percutaneous renal biopsy was performed and showed renal T-cell non-Hodgkin's lymphoma. After six courses of chemotherapy with cyclophosphamide, doxorubicin, vincristine and prednisolone (CHOP) therapy, there was no evidence of lymphoma in this patient.