Peritoneal Dialysis-Related Fungal Peritonitis: Twenty-Year Experience of a Medical Center in Southern Taiwan

Deng-Chi Yang ； Ming-Cheng Wang ； Wei-Hung Lin ； An-Bang Wu ； Junne-Ming Sung ； Meng-Fu Cheng ； Chin-Chung Tseng

《Acta Nephrologica》 26卷3期 (2012/09) Pp. 149-154

https://doi.org/10.6221/AN.2012004

並列摘要

BACKGROUND: Fungal peritonitis is a rare but frequently lethal peritonitis in patients with endstage renal disease (ESRD) receiving peritoneal dialysis (PD). We reported our twenty-year experience of fungal peritonitis, management and outcome, and identified the risk factors associated with mortality.METHODS: We retrospectively screened all patients with ESRD receiving PD at our PD center between 1 January 1990 and 31 December 2009, and identified the patients diagnosed with fungal peritonitis from 1990 to 2009. Records of all patients with fungal peritonitis were carefully reviewed. Clinical information was collected, including age, gender, clinical presentation, causative pathogens, management, and outcomes. Risk factors associated with mortality were also analyzed.RESULTS: The incidence of fungal peritonitis in our series was 0.13 episodes per 100 patientmonths. Candida species were the most common pathogens, accounting for 72% of fungal peritonitis, and Candida tropicalis (27%) was the most common Candida species. All patients with fungal peritonitis had the catheter removed except one who was transferred to the local hospital, and all received antifungal therapy. Three-month mortality was 20%, but technique survival was 15%. The presence of diabetes mellitus (P = 0.032) and advanced age (P = 0.036) predicted mortality. Gender, previous antibiotics use, previous bacterial peritonitis, and serum albumin had no influence on mortality.CONCLUSION: For patients with PD-related fungal peritonitis, attention should be paid to those with diabetes and advanced age owing to higher risk of mortality.

並列關鍵字

peritoneal dialysis ； fungal peritonitis ； outcome ； diabetes mellitus

參考文獻

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