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  • 期刊

Solid and Papillary Neoplasm of the Pancreas: Report of Two Cases

胰臓之實質乳頭狀瘤:二病例報告

摘要


我們報告二例胰臟之實質乳頭狀瘤,分析其臨床與病理表現並回顧相關文獻。兩位患者皆為女性,年齡分別為12歲及37歲。第一例因右上腹痛和嘔吐來就診,腹部超音波及電腦斷層掃描發現胰臟頭部有一個實質性腫瘤。第二例則主訴在左上腹部模到腫塊,影像學檢查發現胰臟尾部有一個囊狀腫瘤。二者皆經手術成功切除腫瘤且未再復發。病理所見,這些腫瘤巨大而外覆莢膜,其結構包括外圍之實質部及中央不同程度之出血性壞死所形成之囊狀部;顯微鏡下,腫瘤內同時有實質狀及乳頭狀之細胞排列。因此,臨床上於年輕女性發現胰臟之有莢膜腫塊時,應把實質乳頭狀瘤之診斷列入考慮,此腫瘤雖然是低度惡性但預後良好,往往可藉由手術切除而加以根治。

並列摘要


We report two rare cases of solid and papillary neoplasm of the pancreas with pathological correlation and a review of the literature. Both patients were female, aged 12 and 37 years respectively. The first case presented with right upper abdominal pain with vomiting. Abdominal sonography and computed tomography examinations showed a heterogeneous soft tissue mass in the pancreatic head. The second case presented with a palpable mass in the left upper abdomen. Imaging studies revealed an almost completely cystic mass with rim calcification in the pancreatic tail. Both tumors were successfully resected without recurrence. Gross examination showed that these tumors were well-encapsulated and exhibited solid peripheral parts with varying degrees of central hemorrhagic necrosis resulting in cystic components. Microscopically, distinct solid and papillary patterns were shown. The diagnosis of solid and papillary neoplasm should be considered in young women presenting with a well-encapsulated mass in the pancreas. Although a low-grade malignancy, this tumor is potentially curable by surgical resection.

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