Clinical Application of 18F-FDG PET and PET/CT in Patients with Head and Neck Cancers

氟-18氟化去氧葡萄糖正子斷層攝影及正子/電腦斷層攝影在頭頸部癌症病患之臨床應用

施並富(Bing-Fu Shih) ； 曹勤和(Chin-Ho Tsao) ； 林谷鴻(Ku-Hung Lin) ； 吳明哲(Ming-Che Wu)

《中華民國癌症醫學會雜誌》 25卷1期 (2009/02) Pp. 3-11

https://doi.org/10.6588/JCOS.2009.25.1.1

摘要

氟-18氟化去氧葡萄糖正子斷層攝影以及正子/電腦斷層攝影逐漸廣泛應用於頭頸部癌症病患。在疾病分期方面，正子斷層攝影以及正子/電腦斷層攝影可以提供有用的臨床資料，特別是關於頸部淋巴分期以及偵測遠端轉移和第二原發惡性腫瘤。對於原發腫瘤部位不明之頸部淋巴轉移病患，正子斷層攝影以及正子／電腦斷層攝影可以幫忙確定腫瘤部位。對於接受放射治療或合併化學與放射治療的病患，正子斷層攝影以及正子／電腦斷層攝影在治療效果評估方面很有幫助。同時，正子斷層攝影以及正子/電腦斷層攝影在偵測腫瘤復發方面準確性高，可以應用於高危險群及臨床懷疑復發的病患。另外，正子斷層攝影以及正子／電腦斷層攝影能夠提供關於存活率的相關預後資訊。至於正子/電腦斷層攝影在放射治療計劃應用方面，目前正在積極研究之中。

關鍵字

正子斷層攝影 ； 頭頸部癌症

並列摘要

Fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) and integrated PET/CT have been increasingly used in patients with head and neck cancers. 18F-FDG PET and PET/CT can provide valuable information during initial staging, especially in the nodal staging of the neck and in the detection of distant metastases or synchronous second primary malignancies. They are also helpful in identifying a primary tumor in patients with cervical lymph node metastases from an unknown primary tumor. PET and PET/CT are useful for the evaluation of treatment response in patients undergoing radiotherapy or chemoradiotherapy. PET and PET/CT are accurate in the detection of recurrent disease and can be used in patients at high risk or with clinically suspected recurrence. In addition, PET and PET/CT can provide independent prognostic information with regard to relapse-free survival and overall survival. The role of PET/CT in the radiotherapy planning has been under active investigation recently.

並列關鍵字

positron emission tomography ； head and neck cancers