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摘要


糖尿病人容易感染特殊的病原菌。感染使糖尿病人的血糖不易控制,而且糖尿病人的抵抗力弱,使得感染的病程延長。鼻腦白黴菌病為一少見而且嚴重的感染症。它易發生於血糖控制不良,或併發酮酸中毒的糖尿病人。延遲診斷及治療常造成高死亡率。此症常先於副鼻竇造成感染,可見黑色壞死組織,然後擴散至腦膜及腦部,造成眼神經麻痺及其他症狀。 本病例報告一位66歲男性糖尿病人,因一星期左右的左眼紅腫而住院,經組織切片檢查證實為一白黴菌病感染。病人接受多次外科清除術,抗黴菌藥物Amphotericin B,總劑量約2克治療,及血糖的控制,病人得以存活,並繼續在門診追蹤。

並列摘要


Rhinocerebral mucormycosis, is a life threatening fungal infection, mainly affect patients with diabetic ketoacidosis or are immunocompromised. We present a 66-year-old male with poorly controlled diabetes with rhinocerebral mucormycosis. The diagnosis was confirmed by the biopsy of the infected tissue after external ethmoidectomy and medial maxillectomy. The patient was successfully treated with repeated radical surgical debridement, Amphotericin B (total dose of 2 gm), and the control of blood gluoose levels.

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