Pulmonary and Rhino-orbito-cerebral Mucormycosis in a Patient with Diabetic Ketoacidosis: A Case Report and Review of the Literature

一位糖尿病酮酸血症患者併發肺部及鼻眼腦白黴菌病：病例報告與文獻回顧

詹景堯(Jing-Yao Jhan) ； 張竣期(Chun-Chi Chang) ； 施穎銘(Ying-Ming Shih) ； 戴蕙君(Hui-Chun Tai) ； 林慶雄(Ching-Hsiung Lin)

《胸腔醫學》 29卷1期 (2014/02) Pp. 32-38

摘要

白黴菌病是一種伺機性黴菌感染，主要發生在糖尿病控制不良、噬中性白血球低下、接受類固醇或者其他免疫抑制劑、及鐵質過度攝取的患者身上。感染開始於鼻部及鼻竇，然後快速的蔓延到肺部、眼部、及腦部內構造。在此我們報告一位糖尿病酮酸血症患者併發肺部及鼻眼腦白黴菌病，以強調早期診斷這個潛在致命性黴菌感染的重要性。我們也回顧最近關於白黴菌病處置的文獻。

關鍵字

糖尿病酮酸血症 ； 白黴菌病 ； 鼻眼腦

並列摘要

Mucormycosis is an opportunistic fungal infection mainly occurring in patients with poorly controlled diabetes mellitus or neutropenia, in recipients of corticosteroids or other immunosuppressive medications, and in those with iron overload. The infection begins in the nose and paranasal sinuses and then rapidly spreads to pulmonary, orbital, and intracranial structures. Herein, we report a case of pulmonary and rhino-orbito-cerebral mucormycosis in a patient with diabetic ketoacidosis to emphasize the importance of an early diagnosis of this potentially fatal fungal infection. We also review the recent literature on the management of mucormycosis.

並列關鍵字

diabetic ketoacidosis ； mucormycosis ； rhino-orbito-cerebral