Choroidal osteoma, a rare, and juxtapapillary tumor, generally occurs unilaterally or bilaterally in healthy young female patients. The tumor may affect vision by extending to the macula area, producing macula involved serous detachment, or inducing subretinal neovascularization. We report a 29-year-old female patient with unilateral choroidal osteoma. Visual acuity was 20/200 in the left eye. Fundus examinations of the left eye showed a well-defined, pale orange, and slightly elevated choroidal lesion. Serous detachment of the macula was also noted. After treating with laser photocoagulation on the tumor surface, the subretinal fluid subsided and the patient’s visual acuity improved. Laser photocoagulation may be effective in decreasing subretinal fluid in eyes affected by choroidal osteoma.