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Intravitreal Bevacizumab Treatment in a Patient with Subfoveal Choroidal Neovascularization Secondary to Choroidal Osteoma

於脈絡膜骨瘤相關之黃斑部下脈絡膜新生血管病患施與眼內注射bevacizumab(癌思停)治療-病例報告

摘要


目的:報導一例脈絡膜骨瘤相關之脈絡膜新生血管患者在接受bevacizumab(癌思停)眼內注射後獲得良好反應。 方法:病例報告:一名51歲男性,因右眼視力減退伴隨變形視求診。經視力,眼底影像紀錄、螢光眼底攝影及視網膜斷層掃描等檢查後於右眼黃斑部發現脈絡膜骨瘤相關之脈絡膜新生血管。與病患討論後施予1.25毫克之bevacizumab(癌思停)眼內注射治療。 結果:患者右眼之視力於四週後自數手指頭進步至20/30,變形視之症狀亦於四週後消失,經過六個月的追蹤後,最終視力保持在20/30。 結論:眼內注射bevacizumab(癌思停)可以治療脈絡膜骨瘤相關之脈絡膜新生血管。

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並列摘要


Purpose: To report the favorable response of choroidal neovascularization associated with choroidal osteoma to a single intravitreal injection of bevacizumab (Avastin). Methods: A 51-year-old male presented with decreased visual acuity and metamorphopsia in his right eye. Fundus photography, fluorescein angiography, indocyanine green angiography, optical coherence tomography, and visual acuity tests were performed. Under the diagnosis of classic choroidal neovascularization secondary to choroidal osteoma, the patient's right eye was treated with a single intravitreal injection of 1.25 mg bevacizumab. Results: Visual acuity in the right eye improved from counting fingers to 20/30. Resolution of both metamorphopsia and choroidal neovascularization were noted at 4 weeks post-treatment. Central foveal thickness decreased from 416 μm to 180 μm. At the final 6-month follow-up, the patient's visual acuity was maintained at 20/30 and he had experienced no complications. Conclusion: Intravitreal injection of bevacizumab can result in the regression of choroidal neovascularization secondary to choroidal osteoma.

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