Effect of Bevacizumab in Macular Drusen-A Case Report

眼內注射Bevacizumab治療黃斑部隱結之療效－病例報告

陳宏彥(Hung-Yen Chen) ； 翁林仲(Lin-Chung Woung) ； 陳純貞(Chun-Chen Chen) ； 劉秀雯(Shiow-Wen Liou) ； 曾國亮(Gow-Lieng Tseng)

《中華民國眼科醫學會雜誌》 48卷3期 (2009/12) Pp. 305-311

https://doi.org/10.30048/ACTASOS.200912.0011

摘要

目的：報告使用眼內注射Bevacizumab治療黃斑部隱結之療效。
方法：病例報告
結果：一名74歲健康男性，之前沒有任何全身性疾病病史。病人主訴左眼視力模糊有數年之久，經眼底檢查及螢光攝影檢查後診斷為左眼老年性黃斑部退化合併黃斑部隱結。病人之後接受三次眼內注射Bevacizumab (2.5mg/0.1ml)治療。治療後我們陸續追蹤最佳矯正視力、眼底檢查及螢光攝影檢查。三個月後眼底檢查及螢光攝影檢查顯示黃斑部隱結消失，病人最佳矯正視力改善。
結論：使用眼內注射Bevacizumab後病人黃斑部隱結消失，最佳矯正視力改善。所以我們建議也許可以使用眼內注射Bevacizumab來治療黃斑部隱結。

並列摘要

Purpose: To report the effect of intravitreal injection of bevacizumab in macular drusen.
Methods: A case report.
Results: A 74 yeas old male patient presented to our clinic with the complaint of decreased visual acuity (OS) for several years. An age-related macular degeneration with macular drusen (OS) was noted during his fundus examination and fluorescein angiography (FAG). He received three intravitreal injection of bevacizumab (2.5 mg/0.1ml) consecutively. Post injection best-corrected visual acuity (BCVA), fundus exam, and FAG findings were carefully followed. Three months after intravitreal injection of bevacizumab, the fundus exam and FAG demonstrated regression of macular drusen with improvement of visual acuity.
Conclusion: Intravitreal injection of bevacizumab regress the macular drusen and improved patient's vision. Therefore, intravitreal injection of bevacizumab may be useful for the treatment of macular drusen.

並列關鍵字

drusen ； age-related macular degeneration ； bevacizumab