Descriptive Analysis of Dyslipidemia in Patients Receiving Health Checkups-A Hospital-based Study

健檢民眾血脂肪異常情況之分析－以醫院為例

賴世偉(Shih-Wei Lai) ； 黃金財(Kim-Choy Ng)

《慈濟醫學雜誌》 17卷1期 (2005/02) Pp. 35-38

https://doi.org/10.6440/TZUCMJ.200502.0035

摘要

Objectives: Dyslipidemia is a risk factor of cardiovascular disease. The prevalence of dyslipidemia has increased progressively in Taiwan. The purpose of this study was to depict the distribution of dyslipidemia in Taichung, Taiwan from 2000 through 2002, and to establish a database for the evidence-based medicine. Materials and Methods: This was a hospital-based, descriptive study. We retrospectively analyzed the patients who received periodic health checkups at the China Medical University Hospital from January 2000 through December 2002. Totally, 3,340 patients were enrolled in this study. They were divided into three age groups, 20-39 years-old, 40-64 years-old and ≥65 years-old. The measurements of blood lipids including total serum cholesterol, triglyceride, low density lipoprotein cholesterol (LDL), and high density lipoprotein cholesterol (HDL) were evaluated. The t test, one-way ANOVA test, and chi-square test were used to analyze the data. Results: There were 1,899 men (56.9%) and 1,441 women (43.1%) included in this study. The mean age was 49.3±12.3 years (range, 20-87 years). In the group aged 20 to 39 years, the prevalence of hypercholesterolemia was 40.2% in men and 21.6% in women (p＜0.001). The prevalence of hypertriglyceridemia was 26.3% in men and 3.6% in women (p＜0.001). The prevalence of high levels of LDL was 40.2% in men and 17.4% in women (p＜0.001). The prevalence of low levels of HDL was 35.9% in men and 10.5% in women (p＜0.001). In the group aged 40 to 64 years, the prevalence of hypercholesterolemia was 47.7% in men and 50.3% in women (p=0.233). The prevalence of hypertriglyceridemia was 28.8% in men and 14.7% in women (p＜0.001). The prevalence of high levels of LDL was 47.0% in men and 42.7% in women (p=0.046). The prevalence of low levels of HDL was 37.0% in men and 12.7% in women (p＜0.001). In the group aged 65 years and over, the prevalence of hypercholesterolemia was 44.2% in men and 58.5% in women (p=0.004). The prevalence of hypertriglyceridemia was 25.1% in men and 23.2% in women (p=0.648). The prevalence of high levels of LDL was 44.2% in men and 49.3% in women (p=0.308). The prevalence of low levels of HDL was 42.7% in men and 20.8% in women (p＜0.00l). Conclusion: The prevalence of dyslipidemia was relatively high among the adults in Taichung from 2000 through 2002. The policies and programs to prevent dyslipidemia must be substantially intensified. We hope this study could provide background information for further studies on the evidence-based medicine of dyslipidemia in Taiwan.

關鍵字

血脂肪異常 ； 證據醫學 ； 盛行率 ； 台中市 ； 臺灣

並列摘要

Objectives: Dyslipidemia is a risk factor of cardiovascular disease. The prevalence of dyslipidemia has increased progressively in Taiwan. The purpose of this study was to depict the distribution of dyslipidemia in Taichung, Taiwan from 2000 through 2002, and to establish a database for the evidence-based medicine. Materials and Methods: This was a hospital-based, descriptive study. We retrospectively analyzed the patients who received periodic health checkups at the China Medical University Hospital from January 2000 through December 2002. Totally, 3,340 patients were enrolled in this study. They were divided into three age groups, 20-39 years-old, 40-64 years-old and ≥65 years-old. The measurements of blood lipids including total serum cholesterol, triglyceride, low density lipoprotein cholesterol (LDL), and high density lipoprotein cholesterol (HDL) were evaluated. The t test, one-way ANOVA test, and chi-square test were used to analyze the data. Results: There were 1,899 men (56.9%) and 1,441 women (43.1%) included in this study. The mean age was 49.3±12.3 years (range, 20-87 years). In the group aged 20 to 39 years, the prevalence of hypercholesterolemia was 40.2% in men and 21.6% in women (p＜0.001). The prevalence of hypertriglyceridemia was 26.3% in men and 3.6% in women (p＜0.001). The prevalence of high levels of LDL was 40.2% in men and 17.4% in women (p＜0.001). The prevalence of low levels of HDL was 35.9% in men and 10.5% in women (p＜0.001). In the group aged 40 to 64 years, the prevalence of hypercholesterolemia was 47.7% in men and 50.3% in women (p=0.233). The prevalence of hypertriglyceridemia was 28.8% in men and 14.7% in women (p＜0.001). The prevalence of high levels of LDL was 47.0% in men and 42.7% in women (p=0.046). The prevalence of low levels of HDL was 37.0% in men and 12.7% in women (p＜0.001). In the group aged 65 years and over, the prevalence of hypercholesterolemia was 44.2% in men and 58.5% in women (p=0.004). The prevalence of hypertriglyceridemia was 25.1% in men and 23.2% in women (p=0.648). The prevalence of high levels of LDL was 44.2% in men and 49.3% in women (p=0.308). The prevalence of low levels of HDL was 42.7% in men and 20.8% in women (p＜0.00l). Conclusion: The prevalence of dyslipidemia was relatively high among the adults in Taichung from 2000 through 2002. The policies and programs to prevent dyslipidemia must be substantially intensified. We hope this study could provide background information for further studies on the evidence-based medicine of dyslipidemia in Taiwan.

並列關鍵字

dyslipidemia ； evidence-based medicine ； prevalence ； Taichung ； Taiwan