The Repeatability of Retinal Nerve Fiber Layer and Macular Thickness Measurements Before and After Pupillary Dilation Using Optical Coherence Tomography

散瞳前後對光學同軸眼底斷層掃描儀測量視網膜視神經纖維層及黃斑部厚度測量值的可重複性

徐聖曜(Sheng-Yao Hsu) ； 吳永康(Yung-Kang Wu) ； 童逸楨(I-Chen Tung) ； 蔡榮坤(Rong-Kung Tsai)

《慈濟醫學雜誌》 18卷2期 (2006/04) Pp. 109-112

https://doi.org/10.6440/TZUCMJ.200604.0109

摘要

目的：本研究探測瞳孔效應對光學同軸眼底斷層掃描儀，測量視神經乳頭周圍視網膜神經纖維層及黃斑部視網膜厚度測量值的影響。材料與方法：每位正常者任選一眼，由具經驗之操作者用光學同軸眼底斷層掃描儀，測量視神經乳頭周圍視網膜神經纖維層及黃斑部視網膜厚度，並比較瞳孔散大前後的平均厚度測量值。結果：受檢樣本為43位正常受檢者共計43眼，受檢者26位為女性，17位為男性。瞳孔散大前後的平均瞳孔直徑分別為4.6±0.4及7.3±0.5公厘。比較瞳孔散大前後視神經乳頭周圍視網膜神經纖維層及黃斑部視網膜厚度測量值，無論在視神經乳頭上、下、顯、鼻側等四區，6公厘總黃斑部體積及中心凹厚度，以及1公厘、3公厘、6公厘中心凹周圍，其測量值在瞳孔散大前後並無顯著差異。結論：在本研究中，瞳孔散大與否，並不會影響光學同軸眼底斷層掃描儀測量正常眼視神經乳頭周圍視網膜神經纖維層及黃斑部視網膜厚度之測量值。

關鍵字

光學同軸眼底斷層掃描儀 ； 瞳孔散大 ； 視網膜神經纖維層 ； 黃斑部

並列摘要

Objective: To investigate the effect of pupillary dilation on peripapillary retinal nerve fiber layer (RNFL) and macular retinal thickness measurements when using optical coherence tomography (OCT-3). Materials and Methods: A randomly chosen single eye from each normal subject received peripapillary RNFL and macular retinal thickness measurements using OCT-3, by an experienced operator. Average thickness measurements before and after pupillary dilation were compared. Results: Forty-three eyes of 43 subjects (26 females and 17 males) were enrolled. The mean age of the subjects was 31.4±16.3 years (range, nine to 55 years). The mean pupil diameters before and after pupillary dilation were 4.6±0.4 (range, 3 to 6 mm) and 7.3±0.5 (range, 6 to 9 mm), respectively. Comparing the peripapillary RNFL and macular retinal thickness measurements from before and after pupillary dilation, there were no significant differences in superior, inferior, temporal or nasal peripapillary areas; in 6 mm total macular volume and foveal thickness; and in 1 mm, 3 mm and 6 mm perifoveal areas. Conclusion: The peripapillary RNFL and macular retinal thickness measurements showed no significant differences before and after pupillary dilation when using OCT-3, in normal eyes.

並列關鍵字

optical coherence tomography ； pupillary dilation ； retinal nerve fiber layer ； macula