Small Cell Carcinoma of the Uterine Cervix: A Case Report with Emphasis on Cytopathological Findings

子宮頸小細胞癌：一病例報告並著重其細胞學檢查表現

黃隆正(Lung-Cheng Huang) ； 黎治平(Chin-Ping Li) ； 陳正杰(Cheng-Chieh Chen) ； 李進成(Chin-Cheng Lee) ； 朱旆億(Pei-Yi Chu)

《慈濟醫學雜誌》 18卷6期 (2006/12) Pp. 456-461

https://doi.org/10.6440/TZUCMJ.200612.0456

摘要

發生在子宮頸的小細胞上皮癌是一種罕見腫瘤，由於該腫瘤很容易在早期就侵犯到鄰近淋巴結，所以高度侵犯性的臨床進程和不良的預後為此種癌症的特微。外科手術、放射線療法或化學藥物的複合式治療對該腫瘤可達到較佳的效果。基於以上原因，將小細胞上皮癌與其他的子宮頸癌症區別出來是相當重要的。我們報告一位四十五歲子宮頸小細胞上皮癌的女性病人，臨床表現為不正常的生殖道出血。在傳統的和液態薄層製備技術的子宮頸抹片中都表現出小細胞上皮癌典型的細胞學形態。組織病理學檢查也證實了細胞病理學檢查的診斷。正確的診斷和積極的治療在子宮頸的小細胞上皮癌的處置上扮演重要的角色。

關鍵字

小細胞上皮癌 ； 子宮頸 ； 液態薄層製備技術 ； 子宮頸抹片

並列摘要

Small cell carcinoma of the uterine cervix is a rare tumor characterized by a highly aggressive clinical course and poor prognosis due to the high frequency of lymph node involvement at an early stage. Multimodality treatment including surgical intervention, radiotherapy and adjuvant chemotherapy may achieve a better outcome. Therefore, it is important to distinguish small cell carcinoma from other malignant tumors of the uterine cervix. We describe a 45-year-old female patient who presented with abnormal vaginal bleeding. Both conventional and liquid-based Pap smears showed the characteristic morphological features of this tumor. Histopathological examination further confirmed the diagnosis. In conclusion, accurate diagnosis and aggressive treatment play an important role in the management of small cell carcinoma of the uterine cervix.

並列關鍵字

small cell carcinoma ； uterine cervix ； liquid-based preparation ； Pap smear