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The epithelioid variant of angiomyolipomas has been documented to have the ability to behave in an aggressive manner. We report a 38-year-old woman who presented with progressive left flank pain for several months. A renal angiomyolipoma with hemorrhage was diagnosed with an imaging study, and she underwent surgical removal due to persistent symptoms. Epithelioid features were observed in the histologic examination. Positive immunostaining for HMB-45 further supported the diagnosis. Although the postoperative period in this patient was uneventful after 9 months of follow-up, regular postoperative surveillance is significant in light of the malignant potential of epithelioid angiomyolipomas.

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