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Ampulla Cardiomyopathy (Takotsubo Cardiomyopathy) in a Patient with Diabetic Ketoacidosis: A Case Report

壺腹形心肌病變發生於酮酸中毒病人:個案報告

摘要


壺腹形心肌病變是一種徵候群,包括急性及短暫性左心室功能異常,其特徵為心尖收縮無力,心臟底部收縮正常,但卻無任何冠狀動脈阻塞之病兆。這種徵候群之症狀及徵象與急性心肌梗塞相似,例如,心電圖之變化(ST段上升和T波倒置)和異常心肌酵素。許多造成此徵候群之病因在過去十年來已被廣泛探討,但真正的致病原因仍然不明。臨床之預後通常良好。我們報告一個由酮酸中毒所引發壺腹型心肌病變於七十一歲女性之個案。我們認為兒茶酚胺所引發微小循環功能異常為最可能之致病原因。

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並列摘要


Ampulla cardiomyopathy (Takotsubo cardiomyopathy) is a syndrome, consisting of acute-onset, transient, and abnormal left ventricular wall motion with apical akinesis and basal normokinesis without any detectable coronary lesions. The syndrome has symptoms and signs that are similar to acute myocardial infarction, such as electrocardiogram (ECG) changes (ST-segment elevation and subsequent giant T wave inversion) and abnormal myocardial enzymes. There are many etiologies for this syndrome that have been discussed in the past decade, but the precise etiology remains unclear. The clinical prognosis is usually benign. We reported a 71-year-old woman with ampulla cardiomyopathy precipitated by diabeteic ketoacidosis. We propose that catecholamine-related microcirculation dysfunction appears to be the most likely etiology.

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