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  • 期刊

Pulmonary Cryptococcosis in Pregnancy: 2 Cases Report and Review of the Literature

懷孕期併發肺部隱球菌感染症:兩病例報告及文獻回顧

摘要


隱球菌感染症是一種重要之伺機性黴菌感染症。肺部疾病是僅次於腦膜炎第二常見之隱球菌感染症臨床表現。雖然有極多且廣泛之文獻描述肺部隱球菌感症之一般主題,就我們所知卻只有極少有關於肺部隱球菌感染症發生於懷孕期之相關資訊。在這篇文章中我們描述二位平時健康之婦女於懷孕期及產後期發生了肺部隱球菌感染症,同時我們也針對肺部隱球菌感染症之相關主題、先前文獻已報告過之懷孕婦女肺部隱球菌感染症患者的臨床特徵、因懷孕對免疫功能之生理影響、以及懷孕中發生隱球菌感染症之治療方針做了一些文獻回顧。

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並列摘要


Cryptococcosis is an important opportunistic fungal infection. Pulmonary disease is the second most common manifestation of cryptococcosis next to meningitis. Despite extensive literature addressing the general topic of pulmonary cryptococcosis, there is little specific information about its occurrence during pregnancy. Here we report 2 previously healthy women who develop pulmonary cryptococcosis during pregnancy and postpartum period. We also reviewed literature about the general topic of pulmonary cryptococcosis, the characteristics of previously reported cases with pulmonary cryptococcosis during pregnancy, the physiological effect of pregnancy on immune function and the therapeutic approach for the management of cryptococcosis during pregnancy.

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