EFFECTS OF X-IRRADIATION ON THE SERUM PROTEIN, HEPATIC PROTEIN AND NUCLEIC ACIDS IN THE GUINEA PIGS

X射線對豚鼠血清蛋白，肝蛋白和肝核酸之影響

郝道猛(Dou-Mong Hau)

《中華放射線醫學雜誌》 2卷4期 (1977/12) Pp. 327-340

摘要

The effects of X-ray irradiation on the concentration of the serum proteins, the hepatic protein and nucleic acids in the guinea pigs were studied. The results of this study revealed that X-irradiation invariably decreased the concentrations of the hepatic protein, total serum protein and serum albumin. However, the serum globulin of higher-dose animals showed a rebound phenomenon after the thir-the thirteenth day post-irradiation. The results also revealed that the X-rays played a significant inhibitory effect on the hepatic nucleic acids in the guinea pigs (p<0.01), the higher the dosage of X irradiation is, the lower the concentration of hepatic DNA and RNA were. However, .both of them, recovered gradually after the fifth day post-irradiation.

並列摘要

本研究之目的，在探求X射線對豚鼠血清蛋白，肝蛋白及肝核酸之影響。本結果顯示：X射線可使豚鼠之肝內蛋白，血清總蛋白及血清白蛋白濃度降低。然而，高劑量豚鼠組的血清球蛋白濃度，於照後第13天起，反較對照組為高。本結果並顯示：X射線對豚鼠肝內核酸亦有顯著之抑制作用(P<0.01)。照射X射線之劑量愈高，其肝內DNA和RNA的含量就愈低，但於照後第5天起，二者就漸恢復正常。