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Breast Mass due to Dermatohistiocytoma Protuberans: A Case Report

表皮組織細胞瘤引起的乳房腫塊:病例報告

摘要


表皮組織細胞瘤乃是一種罕見的凸起性、纖維性的皮膚腫瘤。它有易於局部復發但甚少轉移,且難以組織學來診斷的特性。臨床上如果適切局部切除,其預後非常良好,所以確認此腫瘤是非常重要的。有很多學者認為診斷需綜合此腫瘤的外觀,臨床表現,以及組織學上的特性。利用超音波來診斷此腫瘤在文獻上很少被報導。我們報告一個五十九歲女姓病例。病人在兩年前的一次健康檢查時,發現左邊乳房一個小腫塊。而這個腫塊於最近有逐漸變大的趨勢,但沒有臨床上的症狀。超音波檢查發現有一個1.1公分大小、音波表現不均勻的腫塊,位於左邊乳房的皮下脂肪層。彩色超音波顯示此腫瘤有明顯的血流,因此高度懷疑是乳房的惡性肉瘤。切片病理檢查發現是表皮組織細胞瘤。

並列摘要


Dermatohistiocytoma protuberans (DHCP) is an uncommon, raised, fibrous tumor of the skin, characterized by a great tendency to recur locally, in frequent metastasis, and difficulty in making a histologic diagnosis. It is very important to recognize this tumor because of excellent prognosis after adequate local excellent prognosis after adequate local excision. Many authors suggested that a diagnosis of this tumor must be made on the basis of the its gross appearance, clinical behavior, and histologic features. Imaging study with ultrasound has rarely been described. We present a 59-year-old female with DHCP of the breast. She found a small nodule in her left breast during a physical check-up 2 years ago. The lesion enlarged recently but caused no symptoms. Ultrasound (US) examination of the left breast revealed a 1.1-cm heterogeneously echogenic nodule located in the subcutaneous fat of the breast. Color Doppler sonography showed significant color flow signals in this lesion. The possibility of a sarcomatous lesion was therefore suspected. Excisional biopsy was performed and the pathological examination of the representative specimen demonstrated a picture of DHCP. No recurrence was seen in 1 year of follow-up.

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