- 期刊
Postirradiation Malignant Fibrous Histiocytoma of the Breast: A Case Report and Review of the Literature
放射治療術後引發乳房惡性纖維組織細胞瘤：病例報告與文獻回顧
摘要
放射治療術後引發之肉瘤為一罕見但已廣為確定之癌症治療晚期效應。一位37歲婦女於7.8年前因乳癌接受放射線治療後，於右側腋下發生惡性纖維組織細胞瘤。由其腫瘤位置、組織病理及免疫組織化學表現、最初治療結束至發病時間間隔等特性分析，此惡性纖維組織細胞瘤可能與先前之放射治療有密切關係。由於放射治療術後引發肉瘤之機率甚低，因此不應列入乳癌病人接受放射治療與否之主要參考因素。對於惡性纖維組織細胞瘤之後續處理，廣泛性之手術切除是目前相當有效之方法。
並列摘要
Postirradiation sarcomas are an unusual but well-recognized late effect of cancer therapy. A 37-year-old female patient presented with malignant fibrous histiocytoma (MFH) of the right axilla, occurring 7.8 years after radiation treatment for infiltrating duct carcinoma of right breast. The location, the histopathologic and immunohistochemical appearance of the tumor, and the time elapsed since the initial treatment make it probable that this tumor is associated with prior radiation treatment. The possibility of postirradiation sarcoma after radiation therapy should not be a major factor influencing treatment decision in the patient with breast cancer. Wide surgical resection of the tumor seems to be an efficient means in the management of this tumor.
延伸閱讀
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