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Prevalence Study of Elastofibroma Dorsi with Retrospective Evaluation of Computed Tomography

以回溯性電腦斷層攝影評估背部彈性纖維瘤的盛行率

摘要


背部彈性纖維瘤是生長在胸壁後外側的良性腫瘤,多半位於肩胛骨下端之內側。背部彈性纖維瘤可雙側發生,而雙側病灶可同時或不同時出現。臨床上,背部彈性纖維瘤的症狀常為生長在後上背部無痛性、生長緩慢的腫塊。組纖學上,可見到脂肪、纖維組織及彈性纖維交織而成的軟組織腫塊。由於在文獻上對於背部彈性纖維瘤的盛行率報告相當分岐,本研究乃藉由回溯性評估電腦斷層影像,以了解背部彈性纖維瘤在台灣的盛行率。結果顯示,在663位因各種原因而接受胸腔電腦斷層檢查的病患中,只有4例出現背部彈性纖維瘤,其中2例為女性2例為男性,1例男性為雙側病灶,餘三例為單側病灶。4例中有3例在接受電腦斷層攝影時臨床上未出現症狀,在追蹤一至三年後,亦未出現與背部彈性纖維瘤有關之症狀。另一例則是因胸壁後外側觸及腫塊而接受電腦斷層檢查,在接受手術切除後四年並未出現復發。本研究顯示,相對於以往在組織學上11%至24%之盛行率報告,背部彈性纖維瘤在台灣是相當罕見的疾病,以電腦斷層檢查所作的回溯性評估,在一般人口中僅有0.6%之盛行率。

並列摘要


Elastofibroma dorsi is a slow growing tumor typically located at the posterior-lateral chest wall between the ribs and the anterior serratus muscle and deep to the inferior angle of the scapula. This lesion can occur bilaterally and may appear asynchronously. Clinically, this pseudotumor presents as a slowly growing painless lump. Histologically, elastofibroma dorsi is a mesenchymal soft tissue tumor intermingled with fat and elastic fibers in a collagenous fibrous background. Since the reported prevalence of elastofibroma dorsi varied widely in the literature, this study is aimed to estimate the prevalence of this lesion with retrospective evaluation of CT images in patients of various clinical conditions. After a retrospective review of 663 Ct files, only four cases with elastofibroma dorsi were found. They were two women and two men. One male was bilaterally involved and the others unilaterally. Of these 4 cases, 3 were asymptomatic about the lesion at the time of CT examination and after one to three-years’ follow-up. The only symptomatic case received CT with complaint of painless back lump. This patient received operative resection and remained symptom-free after four-years’ follow-up. This study showed that the prevalence of elastofibroma dorsi is extremely low in Taiwan (0.6%) based on retrospective review of CT.

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