骨盆腔放射線治療後產生之子宮內膜癌

Uterine Cancer after Radiation Therapy for Cervical Carcinoma

李耀泰(Yiu-Tai Li) ； 陳福民(Fu-Min Chen) ； 陳天惠(Tien-Hui Chen) ； 柯天龍(Tien-Lung Ko) ； 郭宗正(Tsung-Cheng Kuo)

《中華民國婦癌醫學雜誌》 2007年2期 (2007/10) Pp. 7-11

https://doi.org/10.7010/JGO.200710.0007

摘要

放射線治療已被證實可以治療子宮頸癌，同時放射線亦認為可以致癌症。通常定義這類次發性的癌症，必須與原發性部位之病理組織不同，
否則不論二者之時間相隔多久，只能視為原有癌症復發。放射線治療引發之子宮體癌預後多欠佳，主因此類次發性癌症多屬預後不良之組織，如子宮漿液性乳突狀癌和肉瘤，且發現時已爲晚期病灶。因此，經過骨盆腔放射線治療之患者，不管經過多少年的無病灶，仍需小心觀察和追蹤。

關鍵字

子宮頸癌 ； 放射線治療 ； 子宮體癌

並列摘要

Radiation therapy is a proved treatment for cervical carcinoma, however, radiation-induced uterine cancer are described. The mechanism of carcinogenesis by radiation is still unclear. From a pathologic point of view, the second cancer was defined as having a different histogic type from cancer of the primary site, otherwise, it was classified as a recurrence regardless of the length of periods after therapy. The prognosis of patients who develop endometrial cancer is very poor, because patients who develop uterine cancer after radiation are also much more likely to have uterine papillary serous carcinoma and sarcoma, as well as late stage. Therefore, it is important to continue careful annual surveillance even if the patient has been free of disease for many years.

並列關鍵字

Cervical cancer ； Radiation therapy ； Uterine cancer