- 期刊
低危險妊娠性滋養層疾病之治療
The Best Treatment of Low-Risk Nonmetastatic Trophoblastic Disease
摘要
低危險妊娠性滋養層疾病(GTD)係指患者缺乏臨床上高危險因子，或WHO計分分數≦6。通常低危險性GTD只須用一種藥物來治療，但至今仍沒有報告比較過，哪一種藥物爲最理想。經文獻回顧，較理想藥方有3種，即口服methotrexate (MTX)，點滴注射MTX 100mg/平方公尺和脈搏性actinomycin，但以脈搏性actinomycin可能爲最理想。
並列摘要
Patients with nonmetastatic gestational trophoblastic disease who lack any of the clinical high-risk factors or have a WHO risk score loss than 6 have low-risk disease, they can be treated successfully with initial single-agent regimens. However, the best protocol for treating low-risk trophoblastic disease is uncertain. Ramdomized comparisons of these regimens have not been completed. The following regimens were judged to be superior based after the literature review: oral methotrexate, infusional methotreate 100 mg/m^2 and pulse actinomycin, but pulse actinomycin appeared to be the preferred choice.
延伸閱讀
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