人類乳突病毒的垂直傳染

Vertical Transmission of Human Papillomavirus

李耀泰(Yiu-Tai Li) ； 陳福民(Fu-Min Chen) ； 沈仁達(Jen-Ta Shen) ； 郭宗正(Tsung-Cheng Kuo)

《中華民國婦癌醫學雜誌》 2010年1期 (2010/04) Pp. 14-20

https://doi.org/10.7010/JGO.201004.0014

摘要

人類乳突病毒被認爲乃一種性病，在婦女子宮頸癌前病變和子宮頸癌中存在的比例很高。最近研究亦認爲其可不經由性行爲傳染，即包括垂直傳染、水平接觸傳染、或經身體不同部位行自主感染、或間接傳染。病毒可能經子宮頸向上傳染至羊水、胎盤、滋養層細胞、胎膜、臍血至新生兒中。但此等垂直感染之發生率和真正途徑亦未十分明瞭。所以，如胎兒有感染，是經由產道污染或長久的持續感染，需要長期追蹤，作爲日後診治之參考。

關鍵字

人類乳突病毒 ； 垂直感染 ； 胎盤 ； 羊水

並列摘要

Human papillomavirus (HPV), which is thought to be a sexually transmitted disease, is identified in a high proportion of cervical intraepithelial neoplasias and invasive carcinomas of the cervix among women. In addition, there is well documented that non-sexual transmission also occurs. This includes vertical transmission, horizontal transmission, autoinoculation and possibly indirect transmission. The virus could be transmitted by ascending infection into the amniotic fluid, placental trophoblastic cell, fetal membranes, umbilical cord blood and neonates. However, the vertical transmission rates and routes are not well known. Long term follow will also show whether a more careful follow-up of the newborns delivered by HPV-infected mothers will be warranted.

並列關鍵字

Human papillomavirus ； vertical transmission ； placenta ； amniotic fluid