Plasma Cell Meningitis: A Rare Neurological Complication of Multiple Myeloma Requiring a High Index of Suspicion

Purpose: Plasma cell meningitis is an uncommon neurologic complication of multiple myeloma with a very poor prognosis (median overall survival of 3 months).Case Report: We describe a previously heavy treated 54-year-old caucasian female with Bence Jones multiple myeloma who developed, shortly after a good partial response to a third line therapy, a plasma cell meningitis. Intrathecal chemotherapy was give with achievement of a complete response and improvement of her neurologic status, being alive after more than 6 months of follow-up.Conclusion: A high index of suspicion is necessary to diagnose this rae entity since treatment initiation may provide symptomatic relief and improve the quality of life.

並列關鍵字

multiple myeloma ； neurological symptoms ； plasma cell meningitis ； meningeal myelomatosis ； cerebrospinal fluid ； cytology ； immunophenotyping

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Plasma Cell Meningitis: A Rare Neurological Complication of Multiple Myeloma Requiring a High Index of Suspicion

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