Esthesioneuroblastoma (ENB), a very rare tumor, comprises only 3% of intranasal malignant tumors. ENB can occur in all age groups, but has a particularly high prevalence between age 11 to 20 and 51 to 60. The distribution of ENB between genders is roughly equal. As the tumor is rare, the number of ENB cases treated in individual departments is generally quite small. As a consequence, data from large series and follow-up case studies are limited, and optimal treatment remains controversial. We report three cases of ENB treated with three different strategies. The first case was Kadish stage C, in a patient who did not receive any treatment. The second case was Kadish stage B, in a patient who received surgery combined with radiotherapy. The third was Kadish stage A, in a patient who received surgery only. The symptoms, diagnosis, stage, treatment and the prognosis of ENB are discussed.