榮總眼科內因性葡萄膜炎之統計分析

自民國73年1月至75年10月曾經在榮總眼科接受治療之內因性葡萄膜炎計291名。其中男性214名，女性77名。291名病人中榮民占91名(31.3%)。葡萄膜炎的類型為：HLA-B27類型關連性葡萄膜炎118名(40.5%)、貝西氏病43名(14.8%)、原田氏病及交感性眼炎29名(10.0%)、周邊性葡萄膜炎12名(4.1%)、病毒感染性葡萄膜炎11名(3.8%)、Fuchs'虹彩異色性睫狀體炎6名(2.1%)、梅毒性5名、晶體性3名、葡萄膜炎假面症候群2名、急性網膜壞死症2名、偽晶體性2名、結核病性2名、痳瘋病性2名、類肉瘤症1名、後發性多發性軟骨炎1名及糖尿病性1名。無法歸類者51名(17.5%)，其中24名的臨床表現為急性前葡萄膜炎而HLA-B27抗原為陰性。HLA-B27類型關連性葡萄膜炎的平均罹病年齡為38.2±14.9歲，貝西氏病的為32.4±8.9歲，原田氏病的為39.1±16.5歲而周邊性葡萄膜炎的為39.1±13.1歲。兩眼被波及者在貝西氏病有95.3%，在HLA-B27類型關連性葡萄膜炎有49.2%，在HLA-B27陰性急性前葡萄膜炎有41.7%而在周邊性葡萄膜炎有33.3%。被波及之眼中貝西氏病有92.9%的後發率，HLA-B27類型關連性葡萄膜炎有74.4%而HLA-B27陰性急性前葡萄膜炎有67.6%。後發率在貝西氏病最常小於或等於3個月，在HLA-B27類型關連性葡萄膜炎較常半年到1年半間而在HLA-B27陰性急性前葡萄膜較常大於3年。HLA-B27類型關連性葡萄膜炎經過平均8.9年後84.8%的患眼有大於或等於0.5的視力而原田氏病經3.6年有60.9%，周邊性葡萄膜炎經1.9年有43.8%有大於或等於0.5的視力。貝西氏病則經過平均4.2年有51.8%的患眼有小於或等於0.1的視力。

關鍵字

無資料

並列摘要

From January 1984 to October 1986, totally 291 patients of endogenous uveitis were treated at the Veterans General Hospital. There were 214 males and 77 females and 91 (31.3%) of them were veterans. The 291 patients consisted of 118 (40.5%) of HLA-B27-positive AAU, 43 (14.8%) of Behcet's disease, 29(10.0%) of Harada's disease and sympathetic ophthalmia, 12 (4.1%) of peripheral uveitis, 11 (3.8%) of the virus-induced, 6 (2.1%) of Fuchs' heterochromic cyclitis, 5 of syphilis, 3 of the lens-induced, 2 of masquerade syndrome, 2 of acute retinal necrosis, 2 of the pseudophakic, 2 of tuberculosis, 2 of leprosy, 1 of sarcoidosis, 1 of relapsing polychondritis, 1 of the diabetic and 51 (17.5%) of undetermined group. 24 of the undetermined group manifested as AAU and had no HLA-B27 antigen. Average age of onset was 38.2±14.9 of HLA-B27 associated AAU, 32.4±8.9 of Behçet's disease, 39.1± 16.5 of Harada's disease and 39.1± 13.1 of peripheral uveitis. 95.3% of patients of Behçet's disease, 49.2% of HLA-B27-positive AAU, 41.7% of HLA-B27-negative AAU and 33.3% of peripheral uveitis were involved bilaterally. 92.9% of involved eyes of Behçet's, disease, 74.4% of HLA-B27- positive AAU and 67.6% of HLA-B27-negative AAU showed recurrence. Uveitis in Behçet's disease recurred most often once equal to or less than three months, HLA-B27-positive AAU more often half to one and a half year and HLAB27-negative AAU more often more than three years. 84.8% of involved eyes of HLA-B27-positive AAU, 60.9% of Harada's disease and 43.8% of peripheral uveitis had visual acuity equal to or better than 0.5 after an average of 8.9, 3.6, and 1 .9 years respectively. However, after an average of 4.2 years, 51.8% of involved eyes of Behçet's disease had visual acuity equal to or less than 0.1.

並列關鍵字

endogenous uveitis ； Chinese ； clinical statistics

國際替代計量

榮總眼科內因性葡萄膜炎之統計分析

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