Pilocarpine在急性隅角閉鎖性青光眼臨床應用之評估

Clinical Evaluation of Pilocarpine in Acute Angle-Closure Glaucoma

張正忠(Cheng-Jong Chang) ； 高國棟(Kwou-Dong Kao) ； 吳光山(Guang-Shan Wu) ； 文良彥(Liang-Yen Wen)

《中華民國眼科醫學會會刊》 27卷1期 (1988/05) Pp. 221-228

https://doi.org/10.30048/ACTASOS.198805.0040

摘要

36 cases (36 eyes) with acute angle-closure glaucoma were randomly divided into two groups. Study group of 20 eyes were treated without pilocarpine initially, and the controlled group of 16 eyes were treated with intensive instillation of pilocarpine.
The differents between the two groups were no statistical significant at P＞0.05 level (successful rate 90% versus 93.75%) Average I.O.P. after treatment were 11.76 ± 11.96mmHg (study group) and 17.69 ± 4.23mmHg. (control group) Beside many parasympathetic side effects, ”frequent” instillations of pilocarpine may increase the relative pupillary block and exacerbate the attack. In our impression it is better to select ”infrequent” instillations of 1% or 2% pilocarpine to constrict the pupil when I.O.P. was controlled under 30mmHg.

並列摘要

36 cases (36 eyes) with acute angle-closure glaucoma were randomly divided into two groups. Study group of 20 eyes were treated without pilocarpine initially, and the controlled group of 16 eyes were treated with intensive instillation of pilocarpine.
The differents between the two groups were no statistical significant at P＞0.05 level (successful rate 90% versus 93.75%) Average I.O.P. after treatment were 11.76 ± 11.96mmHg (study group) and 17.69 ± 4.23mmHg. (control group) Beside many parasympathetic side effects, ”frequent” instillations of pilocarpine may increase the relative pupillary block and exacerbate the attack. In our impression it is better to select ”infrequent” instillations of 1% or 2% pilocarpine to constrict the pupil when I.O.P. was controlled under 30mmHg.

並列關鍵字

pilocarpine ； acute angle-closure glaucoma ； pupillary block