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Photic Injury of UV, Blue and White Light in Aphakic Monkey

紫外光,藍光及白光在無晶體猴之光損傷

摘要


五隻無晶體恆河猴視網膜用不同能量之紫外光(波長為365nm),藍光(波長為440nm)或白光(波長為260-700nm)照射,其中三眼以10J/平方公分,30J/平方公分及100J/平方公分之角膜照射能量,其波長分別為365nm,440nm及260-700nm,每隻眼之視網膜分別以藍光,紫外光及白光於不同之角膜照射能量(10J/平方公分,30J/平方公分及100J/平方公分)照射九個點,我們發現無晶體猴之視網膜對波長為365nm之紫外光的敏感度約為波長440nm藍光的6.85倍,在高能量之紫外光照射下,視網膜之外核層及內核層細胞大量死亡,而高能量之藍光則可造成視網膜色素上皮細胞之明顯去色素化及色素上皮下紡錘狀細胞塊(Sub-RPE spindle cell plaque)。

關鍵字

無資料

並列摘要


The retinas of 5 aphakic rhesus monkeys were exposed to UV (peak at 365nm), blue (peak at 440nm) or white light (260-700nm) with varying radiant exposures. We used three corneal radiant exposures (10J/cm^2, 30J/cm^2 and 100J/cm^2) on the retinas of 3 eyes with three peak wavelengths as mentioned above. Nine retinal light spots in each eye were inflicted with each of the 3 wavelengths at each of the three intensity levels. The retina was 6.85 times more sensitive to UV light of 365nm wavelength than to blue light of 440nm wavelength. The UV light predominantly caused cell death of both outer and inner nuclear layer (ONL & INL) in high energy dose, while blue light in high energy dose resulted in marked depigmentation of retinal pigment epithelium (RPE) and formation of sub-RPE spindle cell plaque.

並列關鍵字

photic Injury UV blue and white light aphakic retina monkey

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