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Sterile Endophthalmitis Following Intravitreal Triamcinolone Acetonide: Pseudophakia as a Risk Factor
偽晶體症與玻璃體內Triamcinolone Acetonide注射後無菌性眼內炎之關聯性探討
摘要
Purpose: To investigate the incidence and the possible risk factors of sterile endophthalmitis following intravitreal injections of triamcinolone acetonide (IVTA). Methods: A retrospective analysis of patients receiving IVTA at the Far Eastern Memorial Hospital from February 2004 to August 2007 was carried out to evaluate the incidence of sterile endophthalmitis. Medical records were reviewed, including indications of IVTA, Snellen visual acuity, anterior and posterior segment findings, and intraocular pressure before and after the injection. Results: A total of 111 injections were enrolled. Following IVTA, there were eight cases (8/111, 7.21%) diagnosed as sterile endophthalmitis. All eyes with sterile endophthalmitis presented with pseudohypopyon within one week after IVTA. Seven out of eight eyes were pseudophakic. Of these eyes, all but one eye had intact posterior capsule. The occurrence of sterile endophthalmitis was significantly correlated with pseudophakia (p＜0.05), regardless of the integrity of the posterior capsule. Conclusion: Pseudophakia with or without intact posterior capsule plays an important role in sterile endophthalmitis following IVTA.
關鍵字
無資料並列摘要
Purpose: To investigate the incidence and the possible risk factors of sterile endophthalmitis following intravitreal injections of triamcinolone acetonide (IVTA). Methods: A retrospective analysis of patients receiving IVTA at the Far Eastern Memorial Hospital from February 2004 to August 2007 was carried out to evaluate the incidence of sterile endophthalmitis. Medical records were reviewed, including indications of IVTA, Snellen visual acuity, anterior and posterior segment findings, and intraocular pressure before and after the injection. Results: A total of 111 injections were enrolled. Following IVTA, there were eight cases (8/111, 7.21%) diagnosed as sterile endophthalmitis. All eyes with sterile endophthalmitis presented with pseudohypopyon within one week after IVTA. Seven out of eight eyes were pseudophakic. Of these eyes, all but one eye had intact posterior capsule. The occurrence of sterile endophthalmitis was significantly correlated with pseudophakia (p＜0.05), regardless of the integrity of the posterior capsule. Conclusion: Pseudophakia with or without intact posterior capsule plays an important role in sterile endophthalmitis following IVTA.
延伸閱讀
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