胰島素依賴型糖尿病人視網膜症之流行病學

The Epidemiological Study of Retinopathy in Insulin-Dependent Diabetic Mellitus

林嘉理(Chia-Lee Lin) ； 彭文庚(Wen-Keng Peng) ； 蔡世澤(S. T. Tsai) ； 丁偉(David Ding)

《中華民國眼科醫學會會刊》 30卷2期 (1991/12) Pp. 59-64

https://doi.org/10.30048/ACTASOS.199112.0053

摘要

我們分析100位胰島素依賴型糖尿病(I.D.D.M)例，全部取材於台北榮總新陳代謝科定期門診追蹤之病例，其中有視網膜病變者，更定期於眼科現網膜門診檢查與治療。研究發現87%的患者，第一次被診斷為I.D.D.M之年齡小於30歲，平均發病年齡為20.5±13.4歲，平均發病時間為7.29±4.83年。有糖尿病視網膜病變(D.R)者，其平均罹病時間為11.23±5.13年，與D.R者為6.55±4.01年，有顯著統計學之差異。整體D.R之盛行率為13%，其中B.D.R佔7%，P.P.D.R佔3%，P.D.R佔3%。罹病時間在5年內而有D.R者佔7%，而10年以上者佔35%。所有P.D.R變化者罹病時間均在10年以上，平約16年。有糖尿病腎病變(D.N)者，整體盛行率為11%，罹病時問在5年內者佔5%，10年以上者佔25%。其中有D.R合併D.N者比例為39%，明顯地比無D.R而有D.N者之9%為高。I.D.D.M病人之視力和網膜病變之嚴重度有很大關聯，無D.R者有92歸視力大淤0.5，B.D.R者有90%，而所有P.D.R者視力皆小於或等於0.3。

並列摘要

100 patients of Insulin-Dependent Diabetic Mellitus (IDDM) were enrolled in our study and analysed their systemic and eye conditions in a population-bases.
87% of patients with initial diagnosis of diabetes were less than 30 years old. The mean mean age of disease onset is 20+/-13.4 years.
Only 7% of patients had DM retinopathy if who suffered diabetes less than 5 years, but those who had diabetes for 10 years or more, the occurance of retinopathy raised to 35%. The frequency rate of proliferative DM retinopathy is also increased from 0% of former to 3% of latter. The duration od patients suffered diabetes in retinopathy group versus non-retinopathy group is 11.23+/-5.13 years vs 6.55+/-4.09 years, revealing statistic significant.
In our series, 11% of patients developed diabetic nephropathy. However, in those with diabetic retinopathy, the nephropathy happened to 39% of patients.
90% of IDDM cases with Background diabetic retinopathy or non-retinopathy had visual acuity 0.5 or more. And the vision decreased to less than 0.3 when patients developed severe proliferative diabetic retinopathy.

並列關鍵字

Insulin-dependent diabetic Mellitus ； Diabetic retinopathy ； Diabetic nephropathy ； Prevalence rate