點狀內層脈絡膜病變－病例報告

Punctate Inner Choroidopathy-A Case Report

林伯剛(Po-Kang Lin) ； 劉榮宏(Jorn-Hon Liu) ； 林嘉理(Chia-Lee Lin) ； 林振隆(Cheng-Long Lin) ； 林昌平(Chang-Ping Lin)

《中華民國眼科醫學會會刊》 30卷4期 (1991/12) Pp. 185-190

https://doi.org/10.30048/ACTASOS.199112.0158

摘要

我們提出一個臨床上具有反覆發作特徵的點狀內層脈絡膜病變的病例，這位女性病患，24歲時左眼初次發生視力模糊與暗點，26歲時左眼突然出現中心區旁之暗點，同時視力模糊；經投予Prednisolone治療，四週後症狀緩解。一年後類似症狀又發生在右眼，同時有視野缺損及視覺扭曲。右眼的眼底檢查顯示在脈絡膜內層及視網膜色素上皮層有許多細小黃色浸潤斑點。而左眼的眼底檢查顯示許多分立微小之洞穿病灶，伴隨程度不等的色素變化。組織漿蟲，毒漿蟲，及疱疹之抗體檢查均為陰性。病患之右眼在兩年內反覆發作了三次，而且病灶散佈到黃斑部其他區域，其最後檢查視力右眼為6/15，左眼為6/7.5。

並列摘要

We report a case of punctate inner choroidopathy which demonstrated unique clinical picture with relapsing course. The victim suffered from blurred vision, floater, and visual field defect of left eye when she was 24 years old. This young lady was bothered again by sudden onset of blurred vision and paracentral scotoma of left eye 2 years later. Treated with Predinisolone, she recovered after 4 weeks.
Another similar episode attacked right eye one year later. Blurred vision, visual field defect, and metamorphopsia were complained of. Fundoscopy of right eye showed many tiny yellowish-white opaque spots over posterior pole and mid-periphery, some in the shape of chain. The level of the lesions was at inner choroid and RPE. The lesions gradually underwent atrophic change to become chorioretinal scars within months. The left fundus showed numberous small discrete punched-out lesions with pigmentation. Laboratory examination revealed negative results for Histoplasmosis, Toxoplasmosis, and Herpes antibody titer.
She was treated with Prednisolone; however, the right eye disorder relapsed for another 2 times during 2 years follow-up, and new lesions spreaded to other area of macula. The final visual acuity was 6/15, OD; 6/7.5, OS.

並列關鍵字

Punctate choroidopathy