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摘要


本文報告因有潛在性角膜病變如外傷,化學傷後或慢性角膜炎使新生血管侵入角膜,導致脂肪角膜症之病例5位,患眼均為單側進行性,依筆者觀察,似乎年幼患者進行的速度較快。局部檢查可見有不同程度灰白或黃白色角膜浸潤,同時病灶附近均有表淺或深部血管伸入。文中報告的病例,除局部點用類固醇外,針對不同程度之個案,以氬氣鐳射,輪部移植或角膜移植治療,都有相當令人滿意的結果,其中進行角膜移植的病例,並有病理組織切片及特殊染色可供參考。

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並列摘要


We present 5 cases of progressive unilateral lipoidal infiltration of the cornea. Neither evidence of hyperlipidemia nor lipid metabolism disorder. All the patients have a history of previous ocular disease (3 trauma, 1 chemical injury, 1 chronic keratitis) with associated superficial or stromal vascularization. Besides of adequate medical treatment, we tried Argon Laser photocoagulation and limbal autograft transplantation to arrest the corneal neovascularization and the results were encouraging. We also have the pathological study (specimen from case 5) for 20 lipid keratopathy. Oil-red-O stains showed lipid in the cornea, especially in deep stroma, both intracellular and extracellular. The stroma was markedly thickened, disorganized and heavily vascularized. Plasma cells, lymphocytes and histiocytic-like cells surrounded the blood vessels.

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