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早產兒視網膜病變患者屈光狀態之臨床觀察

Clinical Observation of the Refractive Conditions in Cases of the Retinopathy of Prematurity

摘要


本文收集自1988年3月至1990年7月間在彰化基督教醫院住院經眼科檢查有早產兒視網膜病變並繼續在門診追蹤檢查者;其中接受冷凍治療後,其早產兒視網膜病變改善或穩定者有16位31隻眼,而早產兒視網膜病變輕微無冷凍治療者有6位12隻眼,其平均年齡為4歲7個月。經睫狀肌麻痺,眼超音波及間接眼底鏡檢查,其近視、遠視及散光超過1.0D以上分別為14眼(32.6%),12眼(27.9%)及28眼(65.1%)。有冷凍治療和無冷凍治療兩組的出生體重和懷孕週數均無統計差異。而其球面度數分別為-1.6±3.8D及+0.6±1.8D,有統計差異。眼軸長分別為22.5±1.3mm及21.6±0.4mm亦有統計差異。若以球面度數和冷凍治療的點數統計,兩者之問並無線性關係,可見冷凍治療應與其屈光狀態之發育無關。兩眼不等視及高度近視均發生在冷凍治療組,分別為5眼(33%)及6眼(19%)。雖然本文無法證實早產兒視網膜病變與屈光異常的嚴重程度有直接的關聯,然而大部份較嚴重的屈光異常約發生在接受冷凍治療的早產兒,值得進一步的探討。

關鍵字

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並列摘要


From March 1988 to July 1990, there were 22 children with retinopathy of prematurity (ROP) who were diagnosed during admission to CCH, and continued in follow-up at OPD. Of these, 16 cases (31 eyes), regressed well after cryotherapy, while 6 cases (12 eyes) regressed spontaneously without cryotherapy. The mean age of children at follow-up was 4.6 yrs. Under cycloplegic examination, A-scan sonography and indirect ophthalmoscopy, 14 eyes (32.6%), 12 eyes (27.9%) and 28 eyes (65.1%) had myopia, hyperopia and astigmatism greater than 1.0D respectively. No statistically significant difference of birth weight and gestational age was noted between groups with and without cryotherapy. The spherical equivalent between these two groups -1.6±3.8D and +0.6±1.8D respectively, was however significantly different. The axial length between these two groups, (22.5±1.3mm and 21.6±0.4mm respectively) was also significantly different. No linear regression between spherical equivalent and the number of spots of cryotherapy was noted. Anisometropia and high myopia were noted in 5 eyes (33%) and 6 eyes (19%) respectively -all cases had received cryotherapy. The most severe refractive disorders all occured in premature children who had received cryotherapy, even though we did not demonstrate a direct relationship between ROP and the severity of refractive disorders.

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