多胞胎之早產兒視網膜症之臨床研究

藉著多胞胎早產兒眼底檢查探討(1)多胞胎本身是否為早產兒視網膜之危險因子。(2)多胞胎彼此網膜症之相似性。並藉比較不同程度視網膜症之多胞胎臨床資料，探討引起早產兒視網膜症之因子。本研究收集近五年來，台大醫院及國泰醫院住院或出生之多胞胎早產兒，記錄其出生週數、體重，新生兒併發症，氧氣用量等臨床資料及眼底視網膜之變化，統計不同程度之早產兒視網膜症出現頻率，選出視網膜症不同等級之多胞胎組，向比較其臨床資料以決定危險因子。收集資料齊全的40組多胞胎早產兒共83人。有早產兒視網膜病變者21人，佔19%，三級程度或以上者有5人佔6%，與研究非多胞胎之文獻比較，並無明顯差別。在有視網膜症之14組中，其中5組(35.7%)各嬰兒之視網膜症嚴重程度相同，6組(42.8%)相差一級，3組(21.5%)，彼此相差超過一級。另26組無視網膜症。此結果顯示多胞胎本身並非導致視網膜症之因素。比較各早產兒之臨床資料顯示，腦室週邊白質軟化(Periventricular leukomalasia)及嚴重之呼吸窘迫與早產兒視網膜症有關連。

關鍵字

無資料

並列摘要

From Jan. 1990, multiple birth premature infants born or hospitalized in NTUH and Cathay General Hospital were collected. Clinical data including gestational age, birth weight, neonatal complications, oxygen usage, fundus changes and treatment methods were recorded; frequency of ROP in different stages, similarities of ROP severity among multiple births were analysed statistically. Identification of risk factors will be made by comparing the clinical data among multiple births who had ROP of at least two stage differences in severity. Fourty groups of multiple birth infants with complete data were analysed. there were totally 83 petents. 21 cases (19%) had ROP, 5 cases (6%) had ROP equal to or greater than stagee Ⅲ. Fourteen groups had ROP. Five groups (35.7%) had ROP with same stage severity between each other in each group. In 6 groups (42.8%), there were one stage difference in severity. In 3 groups (21.5%), there were more than one stage difference. In other 26 groups no ROP were found. The results showed multiple birth perse is not a risk factor for ROP. Analysis of the systemic complication showed periventricular leukomalasia and severe respiratory distress syndrom may be related to ROP.

並列關鍵字

Retinopathy of Prematurity ； multiple birth

國際替代計量

多胞胎之早產兒視網膜症之臨床研究

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