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Indocyanine Green Angiographic Features in Idiopathic Subfoveal Choroidal Neovascularization

不明原因性黃斑部脈絡膜新生血管膜於循血綠眼底攝影術中的表現

摘要


本文收集自1995年9月至1998年5月間,在國立台灣大學附設醫院眼科部接受螢光眼底攝影檢查證實罹患「不明原因性黃斑部下新生血管」的15名病患。此十五名病患同時接受了循血綠眼底攝影術檢查,而發現其在循血綠眼底攝影術的表現共分六類:(1)在九隻眼睛中發現,沿著新生血管膜外有一暗環(2)在九隻眼睛中發現,沿著新生血管膜週邊之脈絡膜血管有腫脹擴張現象(3)在五隻眼睛中發現,新生血管膜在攝影的早期至晚期,均發現顯影之亮點(4)有三隻眼睛只在攝影晚期見到顯影亮點(5)有六隻眼睛在整個攝影期間均無顯影現象(6)有六隻眼睛在攝影晚期有染劑滲漏現象。由這些表現可推論在「不明原因性黃斑部下新生血管」的診斷上,循血綠眼底攝影術上的表現,如病灶旁暗環,螢光亮點,病灶旁脈絡膜血管腫脹,及晚期染劑滲漏等現象,似乎為「不明原因性黃斑部下新生血管」的常見表現。由本研究的結果可知,循血綠眼底攝影術可為診斷「不明原因性黃斑部下新生血管」的輔助檢查之一。

關鍵字

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並列摘要


Purpose: To study the indocyanine green (ICG) angiographic findings in idiopathic subfoveal choroidal neovasulization (ISCNV). Methods: 15 patients (mean age: 33±8years old) with unilateral ISCNV received ICG angiography to identify the precise choroidal abnormalities. Results: The ICG angiographic changes were as followed: 1) a dark rim around the vascular membrane in nine eyes. 2) perilesional choroidal vessel engorgement in nine eyes. 3) hot spots or networks first seen in the early phase, and persisting until the late phase in five eyes. 4) hot spots or networks occurring only in the late phase in three eyes. 5) persistence of hypofiuorescent areas during the early and late phases in six cases. 6) Late phase fluorescein leakage in six cases. Conclusion: These findings seemed to imply that the presence of dark rims, hyperfluorescent spots or networks, and perilesional choroidal vessel engorgement may be characteristic features of ISCNV in ICG angiography. The results of our study indicate that ICG angiography may be suggested as an additional diagnostic tool for ISCNV.

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