虹膜裂(Iridoschisis)是一種罕見的兩側性虹膜基質萎縮及撕裂。大多數原因不明,其中約有半數病例合併青光眼,尤其是隅角閉鎖性;極少數病例合併角膜內皮細胞變性。本科於86年經歷兩例不明原因的虹膜裂,其中一例合併青光眼,且兩例皆有角膜內皮細胞變性;前者施行小樑切除術後一年,眼壓控制良好;後者追蹤一年多,與青光眼變化。虹膜裂國外文獻在數十年來僅百餘例,而國內文厭僅有一外傷性病例。本文提出兩例虹膜裂,並回顧文獻加以整理,提出報告。
Iridoschisis is a disease with uncommon bilateral iris stromal atrophy and cleavage that most often develops in elderly population. The majority of cases are idiopathic and no sex preponderance. Glaucoma occurs in approximately 50 % of the cases, and is usually .of the angle-closure type. Corneal endothelial compromise secondary to iridoschisis had been reported before. We present two cases of iridoschisis of which glaucoma was noted in one of them. Corneal endothelial polymegathism by specular microscopy was also found. The differential diagnosis of iridoschisis included the iridocorneal endothelial syndrome, mesodermal dysgenesis and traumatic iridoschisis. We suggest that it is necessary to follow up for glaucoma damage and corneal decornpensation in patients with iridoschisis.